Cypher VRS Video-Rate AFM

The first and only full-featured video-rate AFM

The Cypher VRS AFM is the first and only full-featured video-rate AFM. Finally, researchers can measure nanoscale dynamic processes at video-rate speeds with all of the resolution, versatility, and ease of use that are the hallmarks of an Asylum Research Cypher AFM.

  • High resolution video-rate imaging at up to 625 lines per second
  • Exceptional ease of use—even at 10 frames per second
  • Full range of modes and accessories —all the capabilities of Cypher ES at normal scan speeds


Webinar: There's No Other AFM Like Cypher - Roger Proksch and Mario Viani provide a thorough review of some of the many features and capabilities that set Cypher AFMs apart from all others
Assembly of collagen fibrils - Collagen is the most abundant protein found in humans and other animals. It assembles in vivo into hierarchical structures found in numerous tissues.
DNase Cleavage of Lambda Digest DNA - The Cypher VRS was used to monitor the action of DNase1 on lambda digest DNA
Dynamics in CTAB hemimicelles - In this experiment The Cypher VRS captured the dynamics of hemicylindrical micelles, formed in a 2 mM CTAB solution, migrating across the surface of HOPG.
Video rate AFM imaging of Celgard - Celgard polypropylene membrane imaged at 2.4 fps in air
Video-rate AFM imaging of polycaprolactone polymer thin film - Imaged at 1.3 fps in air
DNA imaged at 1 fps with double-helix resolution
DNA denaturation - A lambda digest DNA sample was prepared for AFM imaging
Solvent annealing of polymer thin film
High resolution video-rate imaging at up to 625 lines per second
  • Cypher VRS sets a new speed benchmark—at least 10× faster than current “fast scanning” AFMs.
  • Captures data directly to a video format, not individual image frames
  • Capture images at high pixel density (512×512) in just over a second, or reduce scan lines to achieve video rates >10 fps
Exceptional ease of use—even at 10 frames per second
  • blueDrive photothermal excitation makes video-rate AFM simple and stable
  • Scanner is extremely robust and fully sealed against liquid spills for complete reliability
  • Motorized laser and detector alignment makes quick work of instrument setup
Full range of modes and accessories—all the capabilities of Cypher ES at normal scan speeds
  • Includes all of the modes included on the Cypher ES with blueDrive
  • Supports all of the optional modes available on the Cypher ES
  • Compatible with all of the Cypher ES optional accessories
Support that goes above and beyond your expectations
  • Includes a standard two-year comprehensive warranty
  • No-charge technical support and expert applications support for life
  • Extended warranty and repair costs are the lowest in the industry
Included Operating Modes
  • Contact mode
  • Dual AC
  • Dual AC Resonance Tracking (DART)
  • Electrostatic Force Microscopy (EFM)
  • Force curves
  • Force Mapping Mode (force volume)
  • Force modulation
  • Frequency modulation
  • Kelvin Probe Force Microscopy (KPFM)
  • Lateral Force Mode (LFM)
  • Loss tangent imaging
  • Magnetic Force Microscopy (MFM)
  • Nanolithography
  • Nanomanipulation
  • Phase imaging
  • Piezoresponse Force Microscopy (PFM)
  • Switching spectroscopy PFM
  • Tapping mode (AC mode)
  • Tapping mode with digital Q control
  • Vector PFM