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Extracellular Vesicle and Nanoparticle Isolation: Boost Productivity with qEV DXter Automation – Now at a Special Price

Blog Post

qEV DXter for Automated Extracellular Vesicle Isolation

Post publication date:

Tuesday, July 21, 2026

A high-throughput automation platform designed to scale up capacity, reproducibility, and efficiency in qEV-based isolation workflows.

Versatility Beyond Extracellular Vesicles:
Thanks to its compatibility with the various Izon column series (20, 35, and 70 nm), DXter automates with equal precision the isolation of:

Lipid Nanoparticles (LNPs) and Liposomes
Viruses, AAVs, and Virus-Like Particles (VLPs)
Exomeres and Non-Vesicular Protein Complexes

Extracellular vesicle research is rapidly moving beyond small exploratory studies towards larger translational projects, biomarker programmes and diagnostic development. As the number of samples increases, laboratories need isolation workflows that are not only effective, but also scalable, reproducible and easy to standardise.

The qEV DXter from Izon Science has been developed to meet this growing need.

Designed specifically for Izon’s qEV Size Exclusion Chromatography columns, qEV DXter automates key stages of the extracellular vesicle isolation process, including column preparation, buffer addition, sample loading and collection of the purified EV fraction.

By reducing repetitive manual operations, the system helps laboratories increase processing capacity while limiting operator-dependent variability and the risk of manual error.

Scale Up Your Extracellular Vesicle Isolation with qEV Automation

Process Up to 24 qEVsingle and 12 qEVoriginal Columns per Run

qEVsingle and qEVoriginal Columns for qEV DXter Automation

qEV DXter can process up to 24 qEVsingle (150 mL volume) or up to 12 qEVoriginal (500 mL volume) columns in parallel, depending on the selected workflow and column format.

This flexibility makes the platform suitable for laboratories working with different sample volumes and throughput requirements, while maintaining the established qEV Size Exclusion Chromatography workflow.

A typical processing cycle takes approximately 45 to 90 minutes, depending on the selected workflow and processing steps. Additional configurations and sample-processing operations can also be discussed according to the laboratory’s requirements.

For laboratories working with larger cohorts, biobank samples or repeated processing schedules, this parallel capacity can significantly increase daily productivity without requiring the team to perform every liquid-handling step manually.

Automate the Most Repetitive Steps of EV Isolation

qEV DXter can automate the main stages of the qEV isolation workflow, including:

column preparation;
buffer addition;
sample pipetting;
collection of the isolated EV fraction.

Automating these operations can reduce hands-on time and help minimise errors associated with repetitive manual pipetting and fraction collection.

This can be especially valuable in multi-user laboratories, where greater process consistency is needed across different operators, projects and processing days.

Compact, Precise and Designed for Reliable Liquid Handling

qEV DXter Internal Workflow Deck for Automated EV Isolation

The system combines a configurable robotic gantry with advanced pipetting technology in a compact platform intended for standard laboratory environments.

A precision glass syringe supports accurate and reproducible pipetting, while the robotic gantry moves components and liquid-handling tools with controlled precision. According to Izon Science, these elements were selected to support accuracy, reproducibility and long-term reliability.

The result is an automated platform designed to bring higher throughput to EV isolation without requiring an excessively large laboratory footprint.

Preserve the qEV Workflow You Already Know

For laboratories already using qEV columns, adopting automation should not necessarily mean abandoning established protocols, consumables or accumulated expertise.

qEV DXter enables research teams to scale their current qEV workflow rather than replacing it with an unrelated isolation method. This continuity can be particularly important when processing:

longitudinal clinical cohorts;
samples from ongoing biomarker studies;
biobank collections;
multi-centre research projects;
studies requiring comparison with previously generated data;
workflows already optimised around qEV columns.

Maintaining consistency in isolation materials and procedures may help laboratories reduce unnecessary methodological changes between historical and future sample sets.

A Flexible Platform for Different Laboratory Requirements

Although qEV DXter is designed around a standard qEV isolation workflow, several parameters can be adapted according to the application.

Customisable options may include:

liquid volumes;
pipetting speeds;
timed workflow steps;
additional sample-processing operations;
optional column-cleaning procedures for reuse scenarios.

Izon Science states that additional workflow features and custom processing steps can be incorporated on request.

This flexibility allows laboratories to discuss an automation configuration aligned with their sample type, throughput requirements and research objectives.

Supporting Research, Translational Studies and Diagnostic Development

qEV columns are already used in extracellular vesicle research across universities, hospitals, clinical research centres and biomedical laboratories.

In Italy, the qEV workflow is well established among research groups working in academic, hospital and IRCCS environments. qEV DXter provides these laboratories with a route towards greater automation while preserving the qEV technology and workflows with which their teams are already familiar.

The platform may be particularly relevant for:

extracellular-vesicle biomarker programmes;
translational and clinical research;
diagnostic assay development;
high-volume sample cohorts;
biobank processing;
laboratories seeking greater workflow standardisation;
research groups moving from exploratory studies to larger-scale projects.

Izon positions the system in particular for growing EV diagnostic developers that require greater isolation capacity and parallel processing.

More Than an Instrument: An Integrated qEV Ecosystem

The value of qEV DXter extends beyond automation alone.

The system forms part of the wider Izon Science qEV platform, allowing laboratories to combine automated processing with a portfolio of qEV Size Exclusion Chromatography columns, established protocols and dedicated technical support.

For existing qEV users, this means that previous investments in workflow development, staff training and experimental optimisation can become the foundation of a more scalable isolation process.

Rather than forcing laboratories to migrate to an entirely different consumable ecosystem, qEV DXter supports the continued use of the qEV workflow while increasing capacity and reducing manual intervention.

A Competitive Automation Opportunity for Italian qEV Users

As new EV isolation platforms enter the market, laboratories should evaluate more than the initial acquisition conditions of an instrument.

Important long-term considerations include:

compatibility with established protocols;
continuity with previous datasets;
future availability of consumables;
processing capacity;
workflow flexibility;
technical and application support;
the risk of becoming dependent on a restricted consumable format.

To support Italian laboratories considering EV workflow automation, Schaefer SEE Srl is making qEV DXter available under particularly competitive commercial conditions.

The objective is to help existing and prospective qEV users adopt automation without giving up the column technology, protocols and expertise they already trust.

Take the Next Step in qEV Automation

qEV DXter brings together the established qEV Size Exclusion Chromatography workflow and automated, parallel sample processing in a platform designed for modern extracellular vesicle laboratories.

With capacity for up to 24 qEVsingle columns or 12 qEVoriginal columns per run, the system can help laboratories:

increase daily sample-processing capacity;
reduce hands-on time;
minimise repetitive manual operations;
improve workflow consistency;
preserve continuity with existing qEV protocols;
prepare for larger clinical and translational studies.

qEV DXter and the complete Izon Science qEV portfolio are distributed in Italy by Schaefer SEE Srl.

Contact our team to discuss your current extracellular vesicle isolation workflow, identify the most appropriate qEV column format and evaluate whether qEV DXter is suitable for your laboratory.