You would have heard of lipid nanoparticles... those vesicles used to develop mRNA vaccines against the COVID-19 pandemic – but what other applications do they have?
Join Michele from Izon Science as she looks into the world of Lipid...
particle size
All the articles in our blog about particle size
Wednesday, August 23, 2023
Tuesday, March 14, 2023
NEW PRODUCT LAUNCH
From accurate sizing at any sample concentration to highly sensitive aggregate detection, and other applications such as low-volume viscometry or particle shape/load measurement, the need for cutting-edge characterization solutions is greater than ever.
Many of...
Monday, January 9, 2023
Venezia | 6-10 febbraio 2023
Come visit us at our stand at the "XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular vesicles: from biophysical challenges to translational challenges" event in Venice, from 6 to 9 february. We will present you our scientific and technological offer: new frontiers for your scientific...
Friday, December 30, 2022
Come visit us at the QuantitatEVs workshop in Trento, from the 31st of January to the 2nd of February! We'll have a booth and we'll do a presentation with our partner Izon Science, one of the worldwide leading company in the market of the EV research field.
We'll be there with other...
Wednesday, November 16, 2022
Aula Bottazzi - Università della Campania - Sant'Andrea delle Dame - Via L. De Crecchio 7, 80138 Napoli
CONFERENCE AIMS
Organoid technology currently represents a fundamental tool for both basic and translational research.
Their potential to faithfully recapitulate human disease is the key for biomedical research in the present and in a near future.
The aim of this...
Monday, November 14, 2022
Presenta Dr. Claude Oelschlager del Karlsruhe Institute of Technology
LS Instruments next webinar will take place on Thursday, November 24th at 15:00 (Zürich): Dr. Claude Oelschlager (Karlsruhe Institute of Technology) will be the guest speaker for this event. He will provide an introduction to DWS microrheology, and present direct...
Tuesday, September 20, 2022
The "EVIta connect" workshop aims to facilitate interaction and possible collaboration between the various participating groups in relation to the following issues:
- EV (Biological and technological) Tools,
- Cancer,
- Aging, Inflammation and Neuroscience,
- ...
Monday, August 8, 2022
Despite its common position on supermarket shelves, milk is a biofluid like – and unlike - any other. Its production is under the biological control of various hormones and its composition – though standardised to a certain extent within species – is subject to the influence of disease and the...
Friday, June 24, 2022
In line with the ongoing need for a targeted therapy against SARS-CoV-2, Idris et al. (2021) describe the development of a SARS-CoV-2-targeted siRNA-nanoparticle...
Thursday, May 26, 2022
Dynamic Light Scattering (DLS) is a powerful technique to investigate the properties of a broad range of colloidal and polymeric suspensions. However, standard DLS is typically limited to fully suspended, purely viscous, liquid samples. In non-ergodic...
Monday, May 23, 2022
From Wednesday 8 to Friday 10 June you will find us at the Stem Cell Research Italy congress at the University of Genoa, in via Balbi 5.
This conference focuses is about scientific research in the field of stem cells.
Here's the list of the...
Thursday, January 20, 2022
Schaefer is pleased to present you the new Cordouan's instrument: THETIS. It allows to measure Nanoparticles Size (including Anisotropic ones). For the very first time there's an instrument available in the market which allows to measure easily lenght and width of...
Friday, October 8, 2021
A running measurement on the Exoid - Next generation TRPS instrument.
TRPS continues to provide a pathway to obtaining precise insights into the physical parameters of nanoparticles in biological samples, pharmaceutical products and more. Here, we share a brief wrap-up of recent, peer-reviewed, TRPS-related publications we thought you might be interested in.
...
Tuesday, September 14, 2021
Thursday, September 16, 2021 - 15.00 Europe/Rome
Prof. Matthias Karg from Heinrich-Heine University, Dusseldorf, will be the guest speaker for this event, focused on particle shape characterization.
Friday, September 10, 2021
Da sinistra a destra: Gwennan André-Grégoire Laetitia Guevel, Julie Gavard e Quentin Sabbagh.
Sharing the story of France-based researcher Dr Gwennan André-Grégoire, who is working on unravelling the EV-related pathophysiology of glioblastoma multiforme
Glioblastoma multiforme (GBM) is a highly aggressive and heterogenous primary tumour occurring in the central nervous...
Friday, September 3, 2021
Chirinos-Flores et al., Gelation of amphiphilic janus particles in an apolar medium, Journal of Colloid and Interface Science, 590 (2021) 12-18.
Dynamic Light Scattering analyzes the dynamics of particles in suspension. In gel systems, however, the dynamics of the systems are partially “frozen” due to a network in which the particles are trapped. For such non-ergodic systems, DLS cannot produce reproducible data and an advanced technique...
Monday, April 12, 2021
NanoLab 3D - DLS
Watch a demo video of LS Inistruments NanoLab 3D and see how to perform particle sizing without the typical errors generated by standard DLS instruments!
Spoiler: there is nothing to do. Just pop the sample in and get a result you can trust, in less than a minute!
The NanoLab 3D is a...
Tuesday, March 16, 2021
We're excited to announce the worldwide launch of the Exoid - the next generation tunable resistive pulse sensing (TRPS) instrument. After years in development, the Exoid incorporates the proven accuracy of TRPS into a semi-automated system with improved sensitivity and usability.
Monday, February 22, 2021
We are excited to announce the new upcoming LS Instruments webinar on Thursday, February 25th at 15:00 with Prof. Frank Scheffold (University of Fribourg). This is the perfect opportunity to learn everything about the Modulated 3D technology: follow the link below to register!
...
Monday, November 23, 2020
Extracellular vesicles have been shown to contribute to the metastasis of melanoma and to the spread of viral infection. We discuss their potential in diagnostics and personalised medicine.
With the rapid expansion of the field of extracellular vesicle (EV) research,...
Monday, October 26, 2020
TRPS is the only technology which accurately delivers concentration of particles per unit volume across a defined particle size, accurate size distribution of these particles and simultaneous measurement of particle surface charge. Thus, reagent quality and sample preparation...
Monday, September 28, 2020
The field of extracellular vesicles (EVs) is continuously expanding with applications in biomarker discovery, rapid diagnostics, potential vaccine candidates and as vehicles of drug delivery. One of the major challenges for their application in a clinical setting is finding a scalable EV...
Monday, August 3, 2020
LS Instruments - DWS Rheolab
Check out this new article from Nick Hawkins & collaborators at the University of Oxford!
Novel co-spray drying technology was used to generate co-amorphous salts against biofilms. LS Instruments' ...
Monday, June 22, 2020
Microgels based on thermally responsive polymers have been widely investigated in the context of controlled release applications. A challenge is to target the release of active ingredients while the bioavailability is maintained, thus preventing the premature degradation of the drug. Recently,...
Thursday, April 30, 2020
Cypher VRS Video-Rate AFM
Atomic Force Microscopy (AFM) is a uniquely powerful tool for virology research. High-resolution imaging techniques, including both AFM and electron microscopy, can easily resolve the size and shape of virus particles and even the organization of capsomeres in their capsid protein shells...
Monday, April 27, 2020
qNano Gold by Izon Science
Evidence implicating the pivotal role of Extracellular Vesicles (EVs) in stimulation of tissue regeneration is rapidly gaining pace. EVs have been explored as therapeutics for prospective clinical studies1. However, with the current state of affairs, EV production...
Wednesday, April 22, 2020
Cordouan Technologies – VASCO NP size analyzer
Here's a recent publication about the characterization of an HIV nanoparticle-based vaccine using DLS and AF4. This research was conducted by several groups in France and Spain and they used Cordouan's...
Wednesday, April 15, 2020
Analyse thousands of viral particles in just 15 minutes.
TRPS enables rapid quantitation and analysis of individual virus particles in real-time, ideal for assessment of viral titre and aggregation. Measurement takes a matter of minutes and each measurement only requires 40µL of sample...
Wednesday, March 4, 2020
Dr. Nagarjun Konduru and the team at The University of Texas Health Science Center at Tyler (UT Health)
50 million people across the world are struggling with occupational or workplace related lung diseases, says the World Health Organization, occasionally causing death and disability1. Air-borne nanoparticles (< 100nm) are one of the leading causes of occupational and environmental lung...
Tuesday, October 29, 2019
As per the U.S. National Institute of Health, the human endocannabinoid system (ECS) is actively involved in the homeostasis and physiological processes via cannabinoid receptors present throughout the body. Cannabis sativa extract affects the ECS primarily by the presence of...
Tuesday, October 22, 2019
Schaefer is pleased to announce the availability of the new Cordouan Technologies AMERIGO: an innovative analyzer for the characterization of nanoparticle suspensions combining into the same instrument nanoparticle size, Zeta Potential and remote...
Friday, May 3, 2019
As the EV field continues to advance, so has the need for scalability in EV isolation. Along with the recently released Automatic Fraction Collector, Izon is addressing this need with the new qEV100, a size exclusion...
Monday, January 28, 2019
Continuing advances in the EV field and the discovery of new types of nanosized particles (e.g. exomeres), has lead to researchers wanting more specific and precise EV isolation methods. As part of this process Izon has broadened the qEV platform to make available two different size separation...
Monday, September 10, 2018
- Video Interview - Why Zeta Potential Measurement With TRPS Is The Way Of The Future
TRPS has the unique ability to accurately measure the zeta potential of individual nanoparticles. This is incredibly important when working with samples that are polydisperse in size...
Wednesday, February 14, 2018
The VASCO KIN™ is a new generation of nanoparticle size analyzer combining a unique time-resolved kinetic analysis capability with an optical fiber remote probe for in situ measurement. Based on an innovative proprietary Software Time-Resolved Correlation (STRC) technology,...
Wednesday, December 27, 2017
An important new paper on single particle charge measurement has been published in Scientific Reports and it's worth taking a look at it. An extract from the paper is as follows: "The efficacy of this methodology is demonstrated for a range of biological case studies, including measurements of...
Wednesday, November 22, 2017
Here are 4 reasons why you should be using qEV SEC columns for your EV isolation:
- qEV columns preserve the physical function and biological integrity of your EVs and provide the purest isolation from complex biological samples including serum, plasma, saliva, CSF, urine and cell...
Wednesday, May 24, 2017
From 19. – 22. June 2017, over 400 internationally renowned experts and more than 20 exhibitors will meet for the 21st ETH Conference on Combustion-Generated Nanoparticles.
Testo AG will also be there, and at Booth 12 will be presenting the handheld testo DiSCmini – the smallest...
Wednesday, April 26, 2017
What is the background of your research at GWU?
The focus of our lab is on fundamental as well as biomedical applications of microbubbles, liposomes, polymersomes and phase shift nanodroplets. We study the acoustic response as well as mechanical...
Tuesday, March 21, 2017
We are delighted to announce significant improvements to the Izon Integrated Measurement System (Izon IMS), available from today. The Izon IMS encompasses the use of TRPS instruments, measurement science, reagents, consumables, sample preparation and data analysis. With this new update, TRPS...
Wednesday, January 18, 2017
Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations.
Materials and...
Friday, November 25, 2016
We are glad to inform you that we are offering with every DiSCmini purchase the first service maintenance and calibration for free. This promotion is valid for every new testo DiSCmini purchased until 20th December 2016.
The Diffusion Size Classifier Miniature...
Tuesday, November 22, 2016
We are pleased to announce the release and immediate availability of the new analytical-scale exosome isolation column, the qEVsingle. Based on Size Exclusion Chromatography, the qEVsingle is designed to handle 100μL samples of biological fluids (blood plasma or...
Wednesday, October 12, 2016
The new Application Note regarding EV Analysis for the combined use of standardised, quality assured SEC columns (qEV) with TRPS is now available for download. The combined method is simple and practical and for the first time offers an accurate and standard solution to the separation and...
Friday, July 1, 2016
Extracellular vesicles (EVs) are important mediators of intercellular communication and are involved in the transmission of biological information between cells to regulate a broad range of biological processes. EVs contain proteins, mRNA, and miRNA representing the cell they...
Monday, June 20, 2016
Here below we present you two videos from IZON Science. These are the registrations of two different webinars organized by IZON: the first is about "Characterizing Extracellular Vesicles from Biological Fluids", the second is about "Single-Particle Zeta Potential Determined by TRPS". Those two...
Monday, May 23, 2016
Webinar Date: Jun 2, 2016
Time: 3:00 PM UK time (GMT+1)/8:00 AM PST/11:00 AM EST
Duration: 1 hour
The talk is designed to introduce the field of zeta potentials measurements using TRPS, aimed at research students, undergraduates...
Wednesday, May 11, 2016
From 13. – 16. June 2016, over 400 internationally renowned experts and more than 20 exhibitors will meet for the 20th ETH Conference on Combustion-Generated Nanoparticles.
Testo AG will also be there, and at Booth 12 will be presenting the handheld testo DiSCmini – the smallest...
Tuesday, March 8, 2016
"Lipid Nanoparticle delivery of siRNA to unravel chronic pain"
In this webinar, Dr. Marc-Andre Dansereau from the Université de Sherbrooke will describe how RNAi was used to better understand how the CCL2 chemokine and its receptor, CCR2, contribute to the development of...
Monday, February 29, 2016
Webinar Date: March 10, 2016
Time: 8:00 AM PST/11:00 AM EST/15:00 GMT
Extracellular vesicles (EVs) have emerged as important mediators of...
Wednesday, February 24, 2016
We are delighted to invite you to the 5th Izon Science Research Symposium.
Date: 1st and 2nd September, 2016
Venue: Merton College, Oxford, UK.
Last year’s symposium was a tremendous success with over 15 presentations from...
Friday, February 5, 2016
Things are happening at Precision NanoSystems Inc. (PNI)
With new NanoAssemblr™ product launches throughout 2016, PNI aims to enable microfluidic-based manufacture of nanoparticles across the entire nanomedicine research and development pipeline, from discovery to GMP manufacture.
...
Wednesday, January 20, 2016
Izon Science's qEV Size Exclusion Columns are the fastest and easiest method to isolate extracellular vesicles from cell culture supernatants and complex biological fluids. Unlike other methods, size exclusion chromatography (SEC) is gentle on your samples. Your isolated vesicles will be...
Tuesday, September 29, 2015
The Department of Clinical Chemistry, Academic Medical Centre (AMC) of the University of Amsterdam, Netherlands, has a team led by Dr Rienk Nieuwland who are studying the detection and function of extracellular vesicles...
Tuesday, July 14, 2015
We are pleased to present to all our visitors two interesting articles on the TRPS technology.
The first one is about cell death, it explains how cells die every minute, millions of them. These cells need to be replaced, because they're damaged, diseased, or simply...
Friday, July 10, 2015
A recent publication by the group of Professor Yin at the University of Wisconsin-Madison highlights the advantages of TRPS for the characterisation of viruses (bullet-shaped, about 100nm size). TRPS results were compared to TEM, the current benchmark for virion...
Friday, June 26, 2015
We would like to invite you to register for the 2015 Annual Izon Science Research Symposium.
Date: 10-11 September, 2015
Venue: Merton College, Oxford, United Kingdom
The symposium will focus on advances in research using or...
Wednesday, September 24, 2014
Schaefer SEE is the IZON Science exclusive distributor in Italy. The IZON instruments, qNano, qMicro and qViro-x, work with the TRPS (Tunable Resistive Pulse Sensing) technology, based on the Coulter principle. This technology can provide a multi-parameter...
Tuesday, August 26, 2014
Two examples of studies, supported by scientific publications, realized using the qNano from Izon Science. The qNano is considered by the researcher community a dependable instrument in the field of nanoparticles characterization. The qNano is a reliable and robust instrument, which works with...