You would have heard of lipid nanoparticles... those vesicles used to develop mRNA vaccines against the COVID-19 pandemic – but what other applications do they have?
Join Michele from Izon Science as she looks into the world of Lipid...
All the articles in our blog about nanoparticles
You would have heard of lipid nanoparticles... those vesicles used to develop mRNA vaccines against the COVID-19 pandemic – but what other applications do they have?
Join Michele from Izon Science as she looks into the world of Lipid...
Where: Naples, Maritime Station
The upcoming European Colloid and Interface Society Conference 2023 (...
The development of plasmonic nanoparticles as effective biosensors for disease detection is growing rapidly. These new nanoparticle diagnostic markers are being targeted for diseases not easily detected through PCR, or traditional pathology staining.
Using these new nanoparticle...
CytoViva’s Hyperspectral Microscopy is a highly effective tool for the development of nanoscale vectors for drug delivery. It not only provides label free imaging of these nanoscale vectors and their active pharmaceutical ingredients (API), but also enables...
Enhanced Darkfield Hyperspectral Microscopy enables label-free imaging of nanoparticles in a wide range of environmental matrices, including live cells, tissue, and whole animal organisms.
In this webinar, you will learn the principles behind...
From accurate sizing at any sample concentration to highly sensitive aggregate detection, and other applications such as low-volume viscometry or particle shape/load measurement, the need for cutting-edge characterization solutions is greater than ever.
Many of...
Come visit us at our stand at the "XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular vesicles: from biophysical challenges to translational challenges" event in Venice, from 6 to 9 february. We will present you our scientific and technological offer: new frontiers for your scientific...
Come visit us at the QuantitatEVs workshop in Trento, from the 31st of January to the 2nd of February! We'll have a booth and we'll do a presentation with our partner Izon Science, one of the worldwide leading company in the market of the EV research field.
We'll be there with other...
CONFERENCE AIMS
Organoid technology currently represents a fundamental tool for both basic and translational research.
Their potential to faithfully recapitulate human disease is the key for biomedical research in the present and in a near future.
The aim of this...
LS Instruments next webinar will take place on Thursday, November 24th at 15:00 (Zürich): Dr. Claude Oelschlager (Karlsruhe Institute of Technology) will be the guest speaker for this event. He will provide an introduction to DWS microrheology, and present direct...
As the name suggests, synovial fluid is the friction-minimising fluid from within the capsule of synovial joints. Synovial joints are the most common joint type in the human body, with examples including the hip, knee, and elbow. These joints have a propensity towards arthritides such as...
The "EVIta connect" workshop aims to facilitate interaction and possible collaboration between the various participating groups in relation to the following issues:
CytoViva's enhanced darkfield hyperspectral microscopy enables optical observation and spectral characterization of nanoparticle samples as they interact with cells or tissue. No fluorescent labeling or other alteration of the sample is required with the CytoViva system.
...Despite its common position on supermarket shelves, milk is a biofluid like – and unlike - any other. Its production is under the biological control of various hormones and its composition – though standardised to a certain extent within species – is subject to the influence of disease and the...
Dynamic Light Scattering (DLS) is a powerful technique to investigate the properties of a broad range of colloidal and polymeric suspensions. However, standard DLS is typically limited to fully suspended, purely viscous, liquid samples. In non-ergodic...
From Wednesday 8 to Friday 10 June you will find us at the Stem Cell Research Italy congress at the University of Genoa, in via Balbi 5.
This conference focuses is about scientific research in the field of stem cells.
Here's the list of the...
Research of nano-scale vesicles such as liposomes and exosomes as drug delivery vectors has progressed significantly leading to increasing numbers of FDA clinical trials. Most of these early clinical trial efforts have focused on engineered liposomes carrying a drug or gene...
Schaefer is pleased to present you the new Cordouan's instrument: THETIS. It allows to measure Nanoparticles Size (including Anisotropic ones). For the very first time there's an instrument available in the market which allows to measure easily lenght and width of...
Izon Science has introduced a new qEV column optimised for 1 mL sample loading volumes: the qEV1.
The new column is built with a proprietary, agarose resin which delivers improved separation, compared to the resin used in Izon’s existing range of Legacy columns.
The qEV1 was...
Lysozyme amyloid fibrils can be used as natural bio-flocculants to precipitate contaminants in water. In this process, LS Instruments' #DWS...
TRPS continues to provide a pathway to obtaining precise insights into the physical parameters of nanoparticles in biological samples, pharmaceutical products and more. Here, we share a brief wrap-up of recent, peer-reviewed, TRPS-related publications we thought you might be interested in.
...
Thursday, September 16, 2021 - 15.00 Europe/Rome
Prof. Matthias Karg from Heinrich-Heine University, Dusseldorf, will be the guest speaker for this event, focused on particle shape characterization.
Sharing the story of France-based researcher Dr Gwennan André-Grégoire, who is working on unravelling the EV-related pathophysiology of glioblastoma multiforme
Glioblastoma multiforme (GBM) is a highly aggressive and heterogenous primary tumour occurring in the central nervous...
Dynamic Light Scattering analyzes the dynamics of particles in suspension. In gel systems, however, the dynamics of the systems are partially “frozen” due to a network in which the particles are trapped. For such non-ergodic systems, DLS cannot produce reproducible data and an advanced technique...
The collaborative study, now published in the Journal of Extracellular...
Watch a demo video of LS Inistruments NanoLab 3D and see how to perform particle sizing without the typical errors generated by standard DLS instruments!
Spoiler: there is nothing to do. Just pop the sample in and get a result you can trust, in less than a minute!
The NanoLab 3D is a...
We're excited to announce the worldwide launch of the Exoid - the next generation tunable resistive pulse sensing (TRPS) instrument. After years in development, the Exoid incorporates the proven accuracy of TRPS into a semi-automated system with improved sensitivity and usability.
Extracellular vesicles have been shown to contribute to the metastasis of melanoma and to the spread of viral infection. We discuss their potential in diagnostics and personalised medicine.
With the rapid expansion of the field of extracellular vesicle (EV) research,...
TRPS is the only technology which accurately delivers concentration of particles per unit volume across a defined particle size, accurate size distribution of these particles and simultaneous measurement of particle surface charge. Thus, reagent quality and sample preparation...
Modulated 3D DLS results from Au NPs and BSA interaction. a) Cumulants results, b) CORENN results, were translational and rotational peak are distinguished, c) intensity ratio (rotation/translation) for the nanorods. 0.8 ml of Au NPs suspension, with C = 0.005 mg/ml, are mixed with 16 μl of BSA at C = 1.97 mg/ml.
Protein-nanoparticle suspensions are nowadays widely studied for the development of medical and environmental biosensors. The complexity of interactions between nanoparticles and biological fluids, together with the increasing use of dynamic light scattering (DLS) for their characterization,...
The field of extracellular vesicles (EVs) is continuously expanding with applications in biomarker discovery, rapid diagnostics, potential vaccine candidates and as vehicles of drug delivery. One of the major challenges for their application in a clinical setting is finding a scalable EV...
Check out this new article from Nick Hawkins & collaborators at the University of Oxford!
Novel co-spray drying technology was used to generate co-amorphous salts against biofilms. LS Instruments' ...
Why do we believe FluidFM can help solving some of the most critical challenges in CRISPR cell engineering?
What's the biggest story of Single Cell Analysis for 2019?
What are the biggest issues Genomics and Single Cell Analysis researches face in 2020?
What will 2020 hold for...
Join us on July 15th for a live webinar!
Prof. Samiul Amin (Manhattan College) will be presenting new applications of DWS optical microrheology in cosmetic formulations. The microstructure of surfactant/biosurfactant systems and its characterization through high frequency...
Microgels based on thermally responsive polymers have been widely investigated in the context of controlled release applications. A challenge is to target the release of active ingredients while the bioavailability is maintained, thus preventing the premature degradation of the drug. Recently,...
Atomic Force Microscopy (AFM) is a uniquely powerful tool for virology research. High-resolution imaging techniques, including both AFM and electron microscopy, can easily resolve the size and shape of virus particles and even the organization of capsomeres in their capsid protein shells...
Evidence implicating the pivotal role of Extracellular Vesicles (EVs) in stimulation of tissue regeneration is rapidly gaining pace. EVs have been explored as therapeutics for prospective clinical studies1. However, with the current state of affairs, EV production...
Monday April 27, 2020 - 4:00 PM to 4:45 PM CET
We would like to invite you to learn about CytoViva's patented 3D enhanced darkfield microscopy and its ability to help you visualize nanoparticle uptake and localization in cells and tissue. Whether nanoparticles are...
Here's a recent publication about the characterization of an HIV nanoparticle-based vaccine using DLS and AF4. This research was conducted by several groups in France and Spain and they used Cordouan's...
TRPS enables rapid quantitation and analysis of individual virus particles in real-time, ideal for assessment of viral titre and aggregation. Measurement takes a matter of minutes and each measurement only requires 40µL of sample...
Wednesday, March 25, 2020 from 3:00 PM to 3:45 PM CET
One of the biggest challenges when developing nanoparticles for theranostic applications is understanding how they behave in different biological environments. Join us Wednesday March 25th at 3:00pm...
50 million people across the world are struggling with occupational or workplace related lung diseases, says the World Health Organization, occasionally causing death and disability1. Air-borne nanoparticles (< 100nm) are one of the leading causes of occupational and environmental lung...
Dec 17, 2019 10:00 AM to Dec 17, 2019 11:00 AM
Understanding the response of cells to a compound is crucial for determining their potential uses and effects. However, most of the current methods are neither capable to know whether the samples are delivered inside a single...
The FluidFM nanosyringe has been officially launched. Specifically developed for precision nano-injection directly into the nucleus or the cytoplasm of single adherent cells. The sharp apex with its 600 nm aperture...
As per the U.S. National Institute of Health, the human endocannabinoid system (ECS) is actively involved in the homeostasis and physiological processes via cannabinoid receptors present throughout the body. Cannabis sativa extract affects the ECS primarily by the presence of...
Schaefer is pleased to announce the availability of the new Cordouan Technologies AMERIGO: an innovative analyzer for the characterization of nanoparticle suspensions combining into the same instrument nanoparticle size, Zeta Potential and remote...
As the EV field continues to advance, so has the need for scalability in EV isolation. Along with the recently released Automatic Fraction Collector, Izon is addressing this need with the new qEV100, a size exclusion...
May 21st to May 23rd, 2019
San Raffaele Hospital - Via Olgettina, 48 – 20132 Milano
A new era in exosome and extracellular vesicle (EV) isolation starts this week when the first Automatic Fraction Collectors (AFC...
Continuing advances in the EV field and the discovery of new types of nanosized particles (e.g. exomeres), has lead to researchers wanting more specific and precise EV isolation methods. As part of this process Izon has broadened the qEV platform to make available two different size separation...
The VASCO KIN™ is a new generation of nanoparticle size analyzer combining a unique time-resolved kinetic analysis capability with an optical fiber remote probe for in situ measurement. Based on an innovative proprietary Software Time-Resolved Correlation (STRC) technology,...
An important new paper on single particle charge measurement has been published in Scientific Reports and it's worth taking a look at it. An extract from the paper is as follows: "The efficacy of this methodology is demonstrated for a range of biological case studies, including measurements of...
Here are 4 reasons why you should be using qEV SEC columns for your EV isolation:
Biological cells consist of various subcellular structures, including the nucleus, nucleolus, mitochondria, and the other vesicular structures. The subcellular organelles in cytoplasm have various shapes, and each plays a different role that is crucial for the survival of a cell. It is important...
The Enhanced Darkfield Hyperspectral Microscopy (EDFM-HS) of Cytoviva enables optical observation and spectral characterization of a wide range of nanomaterials as they interact with both biological and materials-based matrixes. No labeling or other special sample preparation is...
From 19. – 22. June 2017, over 400 internationally renowned experts and more than 20 exhibitors will meet for the 21st ETH Conference on Combustion-Generated Nanoparticles.
Testo AG will also be there, and at Booth 12 will be presenting the handheld testo DiSCmini – the smallest...
Today, hundreds of labs involved in nanomaterials synthesis, nano-drug delivery, nano-toxicology and related research use CytoViva’s technology: Enhanced Darkfield Hyperspectral Microscopy enables optical observation and spectral characterization of a wide range of nanomaterials...
What is the background of your research at GWU?
The focus of our lab is on fundamental as well as biomedical applications of microbubbles, liposomes, polymersomes and phase shift nanodroplets. We study the acoustic response as well as mechanical...
We are delighted to announce significant improvements to the Izon Integrated Measurement System (Izon IMS), available from today. The Izon IMS encompasses the use of TRPS instruments, measurement science, reagents, consumables, sample preparation and data analysis. With this new update, TRPS...
Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations.
Materials and...
We are glad to inform you that we are offering with every DiSCmini purchase the first service maintenance and calibration for free. This promotion is valid for every new testo DiSCmini purchased until 20th December 2016.
The Diffusion Size Classifier Miniature...
We are pleased to announce the release and immediate availability of the new analytical-scale exosome isolation column, the qEVsingle. Based on Size Exclusion Chromatography, the qEVsingle is designed to handle 100μL samples of biological fluids (blood plasma or...
A new, groundbreaking method for single cell analysis based on FluidFM® technology allows scientist to investigate the behavior of individual cells in their natural environment. The new method was developed at ETH Zurich and could revolutionize biological research as it opens up a completely new...
The new Application Note regarding EV Analysis for the combined use of standardised, quality assured SEC columns (qEV) with TRPS is now available for download. The combined method is simple and practical and for the first time offers an accurate and standard solution to the separation and...
Schaefer Italy announces the launch of the NanoAssemblrTM SparkTM system by Precision Nanosystems to support nanoparticle researchers developing novel nucleic acid-based nanomedicines, including mRNA and CRISPR/Cas9 therapeutics. The ...
Join the Precision NanoSystems Team for a LIVE broadcast of our Nanomedicines Symposium: Materials, Manufacture and Therapeutic Applications.
Scientific leaders will unite at the symposium to discuss the latest applications, results, and best practices in nanoparticle research and...
Extracellular vesicles (EVs) are important mediators of intercellular communication and are involved in the transmission of biological information between cells to regulate a broad range of biological processes. EVs contain proteins, mRNA, and miRNA representing the cell they...
Here below we present you two videos from IZON Science. These are the registrations of two different webinars organized by IZON: the first is about "Characterizing Extracellular Vesicles from Biological Fluids", the second is about "Single-Particle Zeta Potential Determined by TRPS". Those two...
Microfluidic-mediated self-assembly of liposomes and polymer nanoparticles expands the strategies available to the formulation scientist for the encapsulation and delivery of hydrophobic compounds.
In this webinar Dr. James Taylor and Dr. Shyam Garg will explore the encapsulation of a...
Webinar Date: Jun 2, 2016
Time: 3:00 PM UK time (GMT+1)/8:00 AM PST/11:00 AM EST
Duration: 1 hour
The talk is designed to introduce the field of zeta potentials measurements using TRPS, aimed at research students, undergraduates...
Dr. Shyh-Dar Li is an Associate Professor at Faculty of Pharmaceutical Sciences, University of British Columbia. He holds the Angiotech Professorship in Drug Delivery. His research focuses on engineering nanoparticles for drug targeting to tumors.
In this webinar, he will introduce the...
From 13. – 16. June 2016, over 400 internationally renowned experts and more than 20 exhibitors will meet for the 20th ETH Conference on Combustion-Generated Nanoparticles.
Testo AG will also be there, and at Booth 12 will be presenting the handheld testo DiSCmini – the smallest...
Presenter: Prof. Dan Peer
In this webinar, Professor Dan Peer from Tel Aviv University will talk about the application of microfluidics for the preparation of targeted lipid nanoparticles entrapping siRNAs (RNA-tLNPs) directed towards lymphocytes . Special emphasis will...
"Lipid Nanoparticle delivery of siRNA to unravel chronic pain"
In this webinar, Dr. Marc-Andre Dansereau from the Université de Sherbrooke will describe how RNAi was used to better understand how the CCL2 chemokine and its receptor, CCR2, contribute to the development of...
Webinar Date: March 10, 2016
Time: 8:00 AM PST/11:00 AM EST/15:00 GMT
Extracellular vesicles (EVs) have emerged as important mediators of...
We are delighted to invite you to the 5th Izon Science Research Symposium.
Date: 1st and 2nd September, 2016
Venue: Merton College, Oxford, UK.
Last year’s symposium was a tremendous success with over 15 presentations from...
In this webinar, Professor Pieter Cullis from the University of British Columbia will unpack the application of microfluidics for the preparation of "limit-size" lipid nanoparticle systems including liposomes, nanoemulsions and RNA-lipid nanoparticles (RNA-LNP)...
Things are happening at Precision NanoSystems Inc. (PNI)
With new NanoAssemblr™ product launches throughout 2016, PNI aims to enable microfluidic-based manufacture of nanoparticles across the entire nanomedicine research and development pipeline, from discovery to GMP manufacture.
...
Izon Science's qEV Size Exclusion Columns are the fastest and easiest method to isolate extracellular vesicles from cell culture supernatants and complex biological fluids. Unlike other methods, size exclusion chromatography (SEC) is gentle on your samples. Your isolated vesicles will be...
The Department of Clinical Chemistry, Academic Medical Centre (AMC) of the University of Amsterdam, Netherlands, has a team led by Dr Rienk Nieuwland who are studying the detection and function of extracellular vesicles...
We are pleased to present to all our visitors two interesting articles on the TRPS technology.
The first one is about cell death, it explains how cells die every minute, millions of them. These cells need to be replaced, because they're damaged, diseased, or simply...
A recent publication by the group of Professor Yin at the University of Wisconsin-Madison highlights the advantages of TRPS for the characterisation of viruses (bullet-shaped, about 100nm size). TRPS results were compared to TEM, the current benchmark for virion...
We would like to invite you to register for the 2015 Annual Izon Science Research Symposium.
Date: 10-11 September, 2015
Venue: Merton College, Oxford, United Kingdom
The symposium will focus on advances in research using or...
Schaefer South-East Europe Srl offers at a very interesting price a VASCO 3, DLS (Dynamic Light Scattering) system manufactured by Cordouan Tech, the french company top-class. It's an ex demo version, perfectly working, equipped with the NanoQ software.
This promo...
Schaefer SEE is the IZON Science exclusive distributor in Italy. The IZON instruments, qNano, qMicro and qViro-x, work with the TRPS (Tunable Resistive Pulse Sensing) technology, based on the Coulter principle. This technology can provide a multi-parameter...
Two examples of studies, supported by scientific publications, realized using the qNano from Izon Science. The qNano is considered by the researcher community a dependable instrument in the field of nanoparticles characterization. The qNano is a reliable and robust instrument, which works with...
We would like to Invite you to attend the Third annual Izon research symposium, taking place on the 11th & 12th of September 2014 at Saint Hughs College in Oxford.
The symposium will offer an excellent opportunity to observe and discuss Izon technologies, as well as a chance to...