extracellular vesicles

All the articles in our blog about extracellular vesicles

Wednesday, August 23, 2023
Applications of Lipid Nanoparticles (LNPs) in Nanomedicine

You would have heard of lipid nanoparticles... those vesicles used to develop mRNA vaccines against the COVID-19 pandemic – but what other applications do they have? 

Join Michele from Izon Science as she looks into the world of Lipid...

Wednesday, March 15, 2023
Webinar 17th of March 2023 - Label-Free Imaging of Nanoparticles in Complex Biological Environments With Darkfield Hyperspectral Microscopy

What you will learn:

Enhanced Darkfield Hyperspectral Microscopy enables label-free imaging of nanoparticles in a wide range of environmental matrices, including live cells, tissue, and whole animal organisms.

In this webinar, you will learn the principles behind...

Monday, January 9, 2023
XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular Vesicles: from biophysical to translational challenges

Venezia | 6-10 febbraio 2023

Come visit us at our stand at the "XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular vesicles: from biophysical challenges to translational challenges" event in Venice, from 6 to 9 february. We will present you our scientific and technological offer: new frontiers for your scientific...

Friday, December 30, 2022
QuantitatEVs: Multiscale analyses, from bulk to single vesicle

Come visit us at the QuantitatEVs workshop in Trento, from the 31st of January to the 2nd of February! We'll have a booth and we'll do a presentation with our partner Izon Science, one of the worldwide leading company in the market of the EV research field.

We'll be there with other...

Wednesday, November 16, 2022
34th AICC ANNUAL CONFERENCE – Organoids models of human diseases

Aula Bottazzi - Università della Campania - Sant'Andrea delle Dame - Via L. De Crecchio 7, 80138 Napoli

Organoid technology currently represents a fundamental tool for both basic and translational research.
Their potential to faithfully recapitulate human disease is the key for biomedical research in the present and in a near future.
The aim of this...

Wednesday, November 2, 2022
Vescicole extracellulari del liquido sinoviale

As the name suggests, synovial fluid is the friction-minimising fluid from within the capsule of synovial joints. Synovial joints are the most common joint type in the human body, with examples including the hip, knee, and elbow. These joints have a propensity towards arthritides such as...

Monday, August 8, 2022
Milk Extracellular Vesicles: Isolation, Function and Future Uses

Despite its common position on supermarket shelves, milk is a biofluid like – and unlike - any other. Its production is under the biological control of various hormones and its composition – though standardised to a certain extent within species – is subject to the influence of disease and the...

Thursday, July 21, 2022
Tomocube launches World’s First High-Resolution Holotomography Microscope with an Incoherent Light Source

Ground-breaking technology unlocks label-free 3D and 4D live cell imaging on standard imaging plates for higher-throughput and automated screening applications

A novel optical microscope utilizing incoherent light to generate holographic images of unlabelled live cells...

Thursday, February 17, 2022
HSI System

Research of nano-scale vesicles such as liposomes and exosomes as drug delivery vectors has progressed significantly leading to increasing numbers of FDA clinical trials. Most of these early clinical trial efforts have focused on engineered liposomes carrying a drug or gene...

Thursday, December 30, 2021
qEV1 35nm e 70nm

Izon Science has introduced a new qEV column optimised for 1 mL sample loading volumes: the qEV1.

The new column is built with a proprietary, agarose resin which delivers improved separation, compared to the resin used in Izon’s existing range of Legacy columns.  

The qEV1 was...

Friday, October 8, 2021
A running measurement on the Exoid - Next generation TRPS instrument.

A running measurement on the Exoid - Next generation TRPS instrument. 

TRPS continues to provide a pathway to obtaining precise insights into the physical parameters of nanoparticles in biological samples, pharmaceutical products and more. Here, we share a brief wrap-up of recent, peer-reviewed, TRPS-related publications we thought you might be interested in.

Friday, September 10, 2021
From left to right: Gwennan André-Grégoire Laetitia Guevel, Julie Gavard and Quentin Sabbagh.

Da sinistra a destra: Gwennan André-Grégoire Laetitia Guevel, Julie Gavard e Quentin Sabbagh.

Sharing the story of France-based researcher Dr Gwennan André-Grégoire, who is working on unravelling the EV-related pathophysiology of glioblastoma multiforme

Glioblastoma multiforme (GBM) is a highly aggressive and heterogenous primary tumour occurring in the central nervous...

Tuesday, March 16, 2021
The next generation tunable resistive pulse sensing (TRPS) instrument

We're excited to announce the worldwide launch of the Exoid - the next generation tunable resistive pulse sensing (TRPS) instrument. After years in development, the Exoid incorporates the proven accuracy of TRPS into a semi-automated system with improved sensitivity and usability.

Monday, November 23, 2020
 Il ruolo delle vescicole extracellulari nella comunicazione cellula-cellula nel contesto della malattia

Extracellular vesicles have been shown to contribute to the metastasis of melanoma and to the spread of viral infection. We discuss their potential in diagnostics and personalised medicine.

With the rapid expansion of the field of extracellular vesicle (EV) research,...

Monday, October 26, 2020
 Come misurare in maniera precisa e affidabile le tue nanoparticelle (vescicole extracellulari, esosomi, ecc...) con la TRPS

TRPS is the only technology which accurately delivers concentration of particles per unit volume across a defined particle size, accurate size distribution of these particles and simultaneous measurement of particle surface charge. Thus, reagent quality and sample preparation...

Monday, September 28, 2020
Typical elution profile for the qEVoriginal

The field of extracellular vesicles (EVs) is continuously expanding with applications in biomarker discovery, rapid diagnostics, potential vaccine candidates and as vehicles of drug delivery. One of the major challenges for their application in a clinical setting is finding a scalable EV...

Monday, April 27, 2020
‘Tuned’ Exosomes: Ushering the Era of Acellular Therapy in Regenerative Medicine

qNano Gold by Izon Science

Evidence implicating the pivotal role of Extracellular Vesicles (EVs) in stimulation of tissue regeneration is rapidly gaining pace. EVs have been explored as therapeutics for prospective clinical studies1. However, with the current state of affairs, EV production...

Wednesday, April 15, 2020
Vaccine & Virus Formulation with TRPS technology: the Izon Science's way.

Analyse thousands of viral particles in just 15 minutes.

TRPS enables rapid quantitation and analysis of individual virus particles in real-time, ideal for assessment of viral titre and aggregation. Measurement takes a matter of minutes and each measurement only requires 40µL  of sample...

Wednesday, March 4, 2020
Dr. Nagarjun Konduru and the team at The University of Texas Health Science Center at Tyler (UT Health)

Dr. Nagarjun Konduru and the team at The University of Texas Health Science Center at Tyler (UT Health)

50 million people across the world are struggling with occupational or workplace related lung diseases, says the World Health Organization, occasionally causing death and disability1. Air-borne nanoparticles (< 100nm) are one of the leading causes of occupational and environmental lung...

Tuesday, November 26, 2019
Cytosurge FluidFM nanosyringe

The FluidFM nanosyringe has been officially launched. Specifically developed for precision nano-injection directly into the nucleus or the cytoplasm of single adherent cells. The sharp apex with its 600 nm aperture...

Tuesday, October 29, 2019
Andrew Lucero from TresViva

As per the U.S. National Institute of Health, the human endocannabinoid system (ECS) is actively involved in the homeostasis and physiological processes via cannabinoid receptors present throughout the body. Cannabis sativa extract affects the ECS primarily by the presence of...

Friday, May 3, 2019
qEV100 - The First EV Isolation Column Capable of Running 100 mL Samples

As the EV field continues to advance, so has the need for scalability in EV isolation. Along with the recently released Automatic Fraction Collector, Izon is addressing this need with the new qEV100, a size exclusion...

Monday, April 1, 2019
 Automatic Fraction Collector (AFC) for the qEV SEC column range

A new era in exosome and extracellular vesicle (EV) isolation starts this week when the first Automatic Fraction Collectors (AFC...

Monday, January 28, 2019
Exosome Researchers Welcome the Release of 35nm qEV Isolation Columns

Continuing advances in the EV field and the discovery of new types of nanosized particles (e.g. exomeres), has lead to researchers wanting more specific and precise EV isolation methods. As part of this process Izon has broadened the qEV platform to make available two different size separation...

Monday, September 10, 2018
35nm qEV Columns Launching Soon
  • Video Interview - Why Zeta Potential Measurement With TRPS Is The Way Of The Future
    TRPS has the unique ability to accurately measure the zeta potential of individual nanoparticles. This is incredibly important when working with samples that are polydisperse in size...
Wednesday, December 27, 2017
Analisi del potenziale zeta della singola particella biologica

An important new paper on single particle charge measurement has been published in Scientific Reports and it's worth taking a look at it. An extract from the paper is as follows: "The efficacy of this methodology is demonstrated for a range of biological case studies, including measurements of...

Wednesday, November 22, 2017
qEV - Starter Pack

Here are 4 reasons why you should be using qEV SEC columns for your EV isolation:

  1. qEV columns preserve the physical function and biological integrity of your EVs and provide the purest isolation from complex biological samples including serum, plasma, saliva, CSF, urine and cell...
Tuesday, August 8, 2017
Enhanced Darkfield Hyperspectral Microscopy - Cytoviva at Nanosafety 2017

The Enhanced Darkfield Hyperspectral Microscopy (EDFM-HS) of Cytoviva enables optical observation and spectral characterization of a wide range of nanomaterials as they interact with both biological and materials-based matrixes. No labeling or other special sample preparation is...

Tuesday, March 21, 2017

We are delighted to announce significant improvements to the Izon Integrated Measurement System (Izon IMS), available from today. The Izon IMS encompasses the use of TRPS instruments, measurement science, reagents, consumables, sample preparation and data analysis. With this new update, TRPS...

Wednesday, January 18, 2017

Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations.

Materials and...

Tuesday, November 22, 2016

We are pleased to announce the release and immediate availability of the new analytical-scale exosome isolation column, the qEVsingle. Based on Size Exclusion Chromatography, the qEVsingle is designed to handle 100μL samples of biological fluids (blood plasma or...

Wednesday, October 12, 2016
New application note from Izon Science - Integrated Platform for EV Analysis: SEC (qEV) + TRPS (qNano)

The new Application Note regarding  EV Analysis for the combined use of standardised, quality assured SEC columns (qEV) with TRPS is now available for download. The combined method is simple and practical and for the first time offers an accurate and standard solution to the separation and...

Friday, July 1, 2016
Fast and reliable Isolation of Plasma Extracellular Vesicles with the qEV Size Exclusion Chromatography columns

Extracellular vesicles (EVs) are important mediators of intercellular communication and are involved in the transmission of biological information between cells to regulate a broad range of biological processes. EVs contain proteins, mRNA, and miRNA representing the cell they...

Monday, June 20, 2016
IZON qNano Gold:  Characterizing Extracellular Vesicles from Biological Fluids and Zeta Potential Measurements

Here below we present you two videos from IZON Science. These are the registrations of two different webinars organized by IZON: the first is about "Characterizing Extracellular Vesicles from Biological Fluids", the second is about "Single-Particle Zeta Potential Determined by TRPS". Those two...

Monday, May 23, 2016
Single-Particle Zeta Potential Determined by  TRPS

Webinar Date: Jun 2, 2016
Time: 3:00 PM UK time (GMT+1)/8:00 AM PST/11:00 AM EST
Duration: 1 hour

The talk is designed to introduce the field of zeta potentials measurements using TRPS, aimed at research students, undergraduates...

Tuesday, March 8, 2016
Dr. Marc-Andre Dansereau - Sherbrooke University

"Lipid Nanoparticle delivery of siRNA to unravel chronic pain"

In this webinar, Dr. Marc-Andre Dansereau from the Université de Sherbrooke will describe how RNAi was used to better understand how the CCL2 chemokine and its receptor, CCR2, contribute to the development of...

Wednesday, February 24, 2016
5th Izon Science Research Symposium Announcement - Merton College - Oxford

We are delighted to invite you to the 5th Izon Science Research Symposium.

Date: 1st and 2nd September, 2016

Venue: Merton College, Oxford, UK.

Last year’s symposium was a tremendous success with over 15 presentations from...

Wednesday, January 20, 2016
IZON qEV - Isolation columns

Izon Science's qEV Size Exclusion Columns are the fastest and easiest method to isolate extracellular vesicles from cell culture supernatants and complex biological fluids. Unlike other methods, size exclusion chromatography (SEC) is gentle on your samples. Your isolated vesicles will be...

Tuesday, July 14, 2015
 Andrew Devitt and Allan Cameron, University of Aston

We are pleased to present to all our visitors two interesting articles on the TRPS technology.

The first one is about cell death, it explains how cells die every minute, millions of them. These cells need to be replaced, because they're damaged, diseased, or simply...

Friday, July 10, 2015
IZON Science qNano

A recent publication by the group of Professor Yin at the University of Wisconsin-Madison highlights the advantages of TRPS for the characterisation of viruses (bullet-shaped, about 100nm size). TRPS results were compared to TEM, the current benchmark for virion...

Friday, June 26, 2015
Merton Library, the oldest academic library in the world still in use.

We would like to invite you to register for the 2015 Annual Izon Science Research Symposium.

Date: 10-11 September, 2015

Venue: Merton College, Oxford, United Kingdom

The symposium will focus on advances in research using or...

Wednesday, September 24, 2014
Nanopore Izon Science

Schaefer SEE is the IZON Science exclusive distributor in Italy. The IZON instruments, qNano, qMicro and qViro-x, work with the TRPS (Tunable Resistive Pulse Sensing) technology, based on the Coulter principle. This technology can provide a multi-parameter...

Wednesday, August 13, 2014

We would like to Invite you to attend the Third annual Izon research symposium, taking place on the 11th & 12th of September 2014 at Saint Hughs College in Oxford.

The symposium will offer an excellent opportunity to observe and discuss Izon technologies, as well as a chance to...