extracellular vesicles

What you will learn:

Enhanced Darkfield Hyperspectral Microscopy enables label-free imaging of nanoparticles in a wide range of environmental matrices, including live cells, tissue, and whole animal organisms.

In this webinar, you will learn the principles behind...

Come visit us at the QuantitatEVs workshop in Trento, from the 31st of January to the 2nd of February! We'll have a booth and we'll do a presentation with our partner Izon Science, one of the worldwide leading company in the market of the EV research field.

We'll be there with other...

As the name suggests, synovial fluid is the friction-minimising fluid from within the capsule of synovial joints. Synovial joints are the most common joint type in the human body, with examples including the hip, knee, and elbow. These joints have a propensity towards arthritides such as...

Despite its common position on supermarket shelves, milk is a biofluid like – and unlike - any other. Its production is under the biological control of various hormones and its composition – though standardised to a certain extent within species – is subject to the influence of disease and the...

Research of nano-scale vesicles such as liposomes and exosomes as drug delivery vectors has progressed significantly leading to increasing numbers of FDA clinical trials. Most of these early clinical trial efforts have focused on engineered liposomes carrying a drug or gene...

TRPS continues to provide a pathway to obtaining precise insights into the physical parameters of nanoparticles in biological samples, pharmaceutical products and more. Here, we share a brief wrap-up of recent, peer-reviewed, TRPS-related publications we thought you might be interested in.
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The collaborative study, now published in the Journal of Extracellular...

Extracellular vesicles have been shown to contribute to the metastasis of melanoma and to the spread of viral infection. We discuss their potential in diagnostics and personalised medicine.

With the rapid expansion of the field of extracellular vesicle (EV) research,...

The field of extracellular vesicles (EVs) is continuously expanding with applications in biomarker discovery, rapid diagnostics, potential vaccine candidates and as vehicles of drug delivery. One of the major challenges for their application in a clinical setting is finding a scalable EV...

Analyse thousands of viral particles in just 15 minutes.

TRPS enables rapid quantitation and analysis of individual virus particles in real-time, ideal for assessment of viral titre and aggregation. Measurement takes a matter of minutes and each measurement only requires 40µL  of sample...

The FluidFM nanosyringe has been officially launched. Specifically developed for precision nano-injection directly into the nucleus or the cytoplasm of single adherent cells. The sharp apex with its 600 nm aperture...

As the EV field continues to advance, so has the need for scalability in EV isolation. Along with the recently released Automatic Fraction Collector, Izon is addressing this need with the new qEV100, a size exclusion...

Continuing advances in the EV field and the discovery of new types of nanosized particles (e.g. exomeres), has lead to researchers wanting more specific and precise EV isolation methods. As part of this process Izon has broadened the qEV platform to make available two different size separation...

An important new paper on single particle charge measurement has been published in Scientific Reports and it's worth taking a look at it. An extract from the paper is as follows: "The efficacy of this methodology is demonstrated for a range of biological case studies, including measurements of...

The Enhanced Darkfield Hyperspectral Microscopy (EDFM-HS) of Cytoviva enables optical observation and spectral characterization of a wide range of nanomaterials as they interact with both biological and materials-based matrixes. No labeling or other special sample preparation is...

Background: Understanding the pathogenic role of extracellular vesicles (EVs) in disease and their potential diagnostic and therapeutic utility is extremely reliant on in-depth quantification, measurement and identification of EV sub-populations.

Materials and...

The new Application Note regarding  EV Analysis for the combined use of standardised, quality assured SEC columns (qEV) with TRPS is now available for download. The combined method is simple and practical and for the first time offers an accurate and standard solution to the separation and...

Here below we present you two videos from IZON Science. These are the registrations of two different webinars organized by IZON: the first is about "Characterizing Extracellular Vesicles from Biological Fluids", the second is about "Single-Particle Zeta Potential Determined by TRPS". Those two...

"Lipid Nanoparticle delivery of siRNA to unravel chronic pain"

In this webinar, Dr. Marc-Andre Dansereau from the Université de Sherbrooke will describe how RNAi was used to better understand how the CCL2 chemokine and its receptor, CCR2, contribute to the development of...

We are delighted to invite you to the 5th Izon Science Research Symposium.

Date: 1st and 2nd September, 2016

Venue: Merton College, Oxford, UK.

Last year’s symposium was a tremendous success with over 15 presentations from...

The Department of Clinical Chemistry, Academic Medical Centre (AMC) of the University of Amsterdam, Netherlands, has a team led by Dr Rienk Nieuwland who are studying the detection and function of extracellular vesicles...

A recent publication by the group of Professor Yin at the University of Wisconsin-Madison highlights the advantages of TRPS for the characterisation of viruses (bullet-shaped, about 100nm size). TRPS results were compared to TEM, the current benchmark for virion...

Schaefer SEE is the IZON Science exclusive distributor in Italy. The IZON instruments, qNano, qMicro and qViro-x, work with the TRPS (Tunable Resistive Pulse Sensing) technology, based on the Coulter principle. This technology can provide a multi-parameter...