Label-free imaging

All the articles in our blog about Label-free imaging

Sunday, November 26, 2023
 Explore TomoAnalysis - Holotomography Image Analysis Software

With great enthusiasm, we invite you to an upcoming webinar dedicated to introducing Tomocube's latest innovation: TomoAnalysis v1.7.
TomoAnalysis is a holotomography image analysis software that provides a range of customizable procedures of analysis pipelines to address diverse user needs...

Wednesday, March 15, 2023
Webinar 17th of March 2023 - Label-Free Imaging of Nanoparticles in Complex Biological Environments With Darkfield Hyperspectral Microscopy

What you will learn:

Enhanced Darkfield Hyperspectral Microscopy enables label-free imaging of nanoparticles in a wide range of environmental matrices, including live cells, tissue, and whole animal organisms.

In this webinar, you will learn the principles behind...

Monday, January 9, 2023
XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular Vesicles: from biophysical to translational challenges

Venezia | 6-10 febbraio 2023

Come visit us at our stand at the "XXVII SCHOOL OF PURE AND APPLIED BIOPHYSICS - Extracellular vesicles: from biophysical challenges to translational challenges" event in Venice, from 6 to 9 february. We will present you our scientific and technological offer: new frontiers for your scientific...

Friday, December 30, 2022
QuantitatEVs: Multiscale analyses, from bulk to single vesicle

Come visit us at the QuantitatEVs workshop in Trento, from the 31st of January to the 2nd of February! We'll have a booth and we'll do a presentation with our partner Izon Science, one of the worldwide leading company in the market of the EV research field.

We'll be there with other...

Wednesday, November 16, 2022
34th AICC ANNUAL CONFERENCE – Organoids models of human diseases

Aula Bottazzi - Università della Campania - Sant'Andrea delle Dame - Via L. De Crecchio 7, 80138 Napoli

CONFERENCE AIMS
Organoid technology currently represents a fundamental tool for both basic and translational research.
Their potential to faithfully recapitulate human disease is the key for biomedical research in the present and in a near future.
The aim of this...

Thursday, September 15, 2022
Epifluorescence of PVDF and PLA stained with Nile red in Aurelia sp. ephyrae jellyfish acquired together with holotomogram.

Epifluorescenza di PVDF e PLA colorato con rosso Nilo in Aurelia sp. meduse ephyrae acquisite insieme all'olotomogramma. Entrambi i materiali (colore rosso che rappresenta il canale di fluorescenza; indice di rifrazione 1,42 per PVDF e 1,4 per PLA) sono localizzati all'interno del corpo gelatinoso (intervallo di indice 1,355–1,378) dopo 24 ore di esposizione. Le barre equivalgono a 30 μm.

A new article has just been released: it is the result of the activity done in November 2021, a collaboration with CNR-ISMAR (Genoa UOS) and Schaefer South-East Europe, in which the Tomocube HT-2H has been used to do holotomographic imaging on the samples.

...
Monday, September 5, 2022
AuNPs in Cells

CytoViva's enhanced darkfield hyperspectral microscopy enables optical observation and spectral characterization of nanoparticle samples as they interact with cells or tissue. No fluorescent labeling or other alteration of the sample is required with the CytoViva system. 

...
Thursday, July 21, 2022
Tomocube launches World’s First High-Resolution Holotomography Microscope with an Incoherent Light Source

Ground-breaking technology unlocks label-free 3D and 4D live cell imaging on standard imaging plates for higher-throughput and automated screening applications

A novel optical microscope utilizing incoherent light to generate holographic images of unlabelled live cells...

Wednesday, March 16, 2022
Three-dimensional refractive index and phase map of P. knowlesi-infected RBCs.

Alterations in Plasmodium knowlesi-infected red blood cells were studied using TOMOCUBE, INC.'s HT-1H, published in BMC Parasites & Vectors.

From...

Thursday, February 17, 2022
HSI System

Research of nano-scale vesicles such as liposomes and exosomes as drug delivery vectors has progressed significantly leading to increasing numbers of FDA clinical trials. Most of these early clinical trial efforts have focused on engineered liposomes carrying a drug or gene...

Friday, July 9, 2021

13 lug 2021 11:00 AM CEST

Phase Separation is a field that has been actively researched in recent years. Tomocube's Holotomography brings quantitative analysis using refractive index in phase separation research. Join this webinar,...

Thursday, April 29, 2021
May 3, 2021 - Tomocube Holotomography Webinar: Platelet research using HT

The webinar recording is available.

Until now, platelet imaging was limited to mainly focusing on morphology. Tomocube's Holotomography (HT) technology brings a new perspective to platelet research by providing not only three-dimensional images of platelets, but also...

Monday, January 18, 2021
Seeing LLPS (liquid liquid phase separation) with holotomography

Many researchers were interested in seeing LLPS (liquid liquid phase separation) with holotomography.
We introduce LLPS observed by Tomocube's HT in a publication by Choi et. al. - "Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited...