A study developed with the Tomocube holotomographic microscope ranks among the most-read of 2024

The scientific work by Francesca Sbrana, entitled "Label-free three-dimensional imaging and quantitative analysis of living fibroblasts and myofibroblasts by holotomographic microscopy" and published in the international journal Microscopy Research and Technique, has been ranked in the top 10% of the most-viewed papers in the journal throughout 2024. A recognition that highlights the scientific relevance of the research conducted and the growing interest of the international community in label-free imaging techniques.

The study employed holotomographic microscopy to quantitatively and three-dimensionally analyze fibroblasts and myofibroblasts in living cells, without the use of fluorescent markers. This methodology allows real-time monitoring of parameters such as cell volume, dry mass, and organelle changes during the fibroblast-to-myofibroblast transition, a key process in tissue repair mechanisms and fibrosis development.

Schaefer SEE Srl, exclusive distributor of Tomocube technology in Italy, is pleased with this result and thanks Francesca, our former colleague, for her contribution in demonstrating, through published research, the potential of HT (Holotomography) instruments in applied cell biology.