SEE at AIBG 2026: Cell Biology and Advanced Research Technologies – Label-Free Holotomography, Nanoparticle Purification and Characterization, and 3D Bioprinting

Cells are constantly changing. Their morphology, internal organisation and interactions with their environment evolve during proliferation, differentiation and responses to stress.

Capturing these processes over time is essential for understanding cellular dynamics, but conventional imaging methods may require fluorescent labels or sample preparation procedures that can interfere with natural cell behaviour.

Tomocube's HT-X1 holotomography platform offers a different approach, enabling high-resolution, three-dimensional observation of living cells without the need for fluorescent labelling.

By measuring variations in refractive index, holotomography provides quantitative information about cellular morphology and intracellular structures, including nuclei, mitochondria and lipid droplets.

This approach is particularly relevant for investigating organelle dynamics, cell growth, morphological changes associated with stress, and the development of complex biological systems such as organoids.

While molecular and cellular analysis provides essential insights into biological mechanisms, studying cells within a three-dimensional environment can offer a more representative perspective on how tissues develop and function.

Three-dimensional bioprinting enables researchers to create structured biological models by combining cells, biomaterials and precisely controlled spatial architectures.

Regemat3D's BIO V1 and REG4Life bioprinting platforms offer flexible approaches to biofabrication, supporting the development of customised 3D constructs for tissue engineering and regenerative medicine research.

These technologies are particularly relevant to studies of cell differentiation, cell–matrix interactions and tissue organisation.

By providing greater control over the experimental environment, 3D bioprinting can contribute to research into how cells behave within complex biological structures.