The Izon qEV Zenco system allows for an automated and controlled extracellular vesicle (EV) isolation process.
It is compatible with the qEV2, qEV10, and qEV100 columns, as well as larger customized columns.
Quickly identify the ideal collection volume by purifying the sample and analyzing the UV trace to get a snapshot of the elution profile.
Optimize EV isolation with software that visualizes data on particle peaks, flow rate, pressure, conductivity, pH, and time remaining until the run is completed.
Program the Zenco to automate multiple methods. In one run, you can flush the qEV column, purify a sample, and clean the column after use, preparing it for the next cycle.
As you scale up EV-based product manufacturing, you must navigate the stringent regulations of current Good Manufacturing Practices (cGMP). The qEV Zenco is designed to support an EV isolation process compliant with cGMP, providing the necessary specifications and support to meet these standards.
If cGMP compliance is a priority, our team can assist you with:
- Navigating cGMP requirements from instrument installation to process validation
- Understanding the qEV Zenco Pro specifications critical to cGMP compliance
- Accessing the qEV Zenco Pro software that meets 21 CFR Part 11 requirements
- Implementing a tangential flow filtration system aligned with cGMP standards
Videos
Files
| Attachment | Size |
|---|---|
 qEV-Zenco-(beta)-Spec-Sheet.pdf | 168.98 KB |
| qEV-Zenco-for-cGMP-Compliant-Environments-Spec-Sheet.pdf | 336.38 KB |
Technical Features
Flowpath:
- 8 inlets
- 8 outlets
- In-line air sensor
- Column bypass and reverse flow
UV, pH, and conductivity detection:
- UV: Variable single wavelength (190-400 nm)
- pH: Reading range 3-14
- Conductivity: Reading range 0-999 mS/cm
Pump & pressure:
- Maximum flow rate: 100 mL/min
- Low dead volume minimizes sample loss and dilution
- Maximum pressure: 10 bar
Column compatibility: Compatible with qEV2, qEV10, qEV100, and customized columns designed for approximately 400 mL sample loading volumes.
Software capabilities: Visualize your workflow using the flow path, control column flow (forward, reverse, and bypass), and get real-time feedback from various data visualization options.
Dimensions: The qEV Zenco fits easily into any laboratory with a footprint of 327 x 325 x 406 mm (W x H x D). Weight: 30 kg.